Exploring adverse drug events at the class level

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Exploring adverse drug events at the class level

BACKGROUND While the association between a drug and an adverse event (ADE) is generally detected at the level of individual drugs, ADEs are often discussed at the class level, i.e., at the level of pharmacologic classes (e.g., in drug labels). We propose two approaches, one visual and one computational, to exploring the contribution of individual drugs to the class signal. METHODS Having esta...

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PURPOSE Anticoagulant drugs are among the most common medications that cause adverse drug events (ADEs) in hospitalized patients. We performed a 5-year retrospective study at Brigham and Women's Hospital to determine clinical characteristics, types, root causes, and outcomes of anticoagulant-associated ADEs. METHODS We reviewed all inpatient anticoagulant-associated ADEs, including adverse dr...

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ژورنال

عنوان ژورنال: Journal of Biomedical Semantics

سال: 2015

ISSN: 2041-1480

DOI: 10.1186/s13326-015-0017-1